3-Hydroxymethyl-indazole-1-carboxylic acid tert-butyl ester - Names and Identifiers
Name | 1H-Indazole-1-carboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethylethyl ester
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Synonyms | 3-(Hydroxymethyl)-1H-indazole,N1-BOCprotected tert-Butyl 3-(hydroxymethyl)-1H-indazole-1-carboxylate 3-Hydroxymethyl-indazole-1-carboxylic acid tert-butyl ester 1H-Indazole-1-carboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethylethyl ester 1H-Indazole-1-carboxylic acid, 3-(hydroxyMethyl)-, 1,1-diMethylethyl ester
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CAS | 882188-87-6
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3-Hydroxymethyl-indazole-1-carboxylic acid tert-butyl ester - Physico-chemical Properties
Molecular Formula | C13H16N2O3
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Molar Mass | 248.28 |
Storage Condition | 2-8°C |
3-Hydroxymethyl-indazole-1-carboxylic acid tert-butyl ester - Introduction
1H-Indazole-1-carboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethyl ester(1H-Indazole-1-carboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethyl ester) is an organic compound.
Nature:
1H-Indazole-1-carboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethylethyl ester is a white to light yellow crystal with certain chemical stability. It is soluble in some organic solvents at room temperature, such as ether, methanol and dichloromethane. Its molecular formula is C15H19N3O3 and its relative molecular mass is 289.33g/mol.
Use:
1H-Indazole-1-carboxylic acid, 3-(hydroxymethyl)-, 1,1-dimenthylethyl ester is widely used in organic synthesis. It is a commonly used intermediate that can be used in the synthesis of biologically active compounds, such as drugs and pesticides.
Preparation Method:
Generally, the preparation of 1H-Indazole-1-carboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethylethyl ester is obtained by reacting 1H-indazole carboxylic acid with tert-butyl chloroformate under alkaline conditions. During the reaction, it is necessary to properly control the temperature and reaction time, and use suitable solvents and catalysts.
Safety Information:
the specific safety information of 1H-Indazole-1-carboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethylethyl ester should refer to the relevant chemical safety instructions. In general, it should be stored in a dry, well-ventilated place to avoid contact with oxidants and strong acids. During use, wear appropriate protective equipment to avoid contact with skin and inhalation of dust. If you come into contact with this compound, rinse immediately with plenty of water and seek medical attention.
Last Update:2024-04-09 02:00:48